Primary Human Cardiomyocytes and Cardiofibroblasts Treated with Sera from Myocarditis Patients Exhibit an Increased Iron Demand and Complex Changes in the Gene Expression

Primary Human Cardiomyocytes and Cardiofibroblasts Treated with Sera from Myocarditis Patients Exhibit an Increased Iron Demand and Complex Changes in the Gene Expression

Cardiac fibroblasts and cardiomyocytes are the main cells involved in the pathophysiology of myocarditis (MCD). These cells are especially sensitive to changes in iron homeostasis, which is extremely important for the optimal maintenance of crucial cellular processes. However, the exact role of iron...

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Bibliographic Details
Main Authors: Kamil A. Kobak, Paweł Franczuk, Justyna Schubert, Magdalena Dzięgała, Monika Kasztura, Michał Tkaczyszyn, Marcin Drozd, Aneta Kosiorek, Liliana Kiczak, Jacek Bania, Piotr Ponikowski, Ewa A. Jankowska
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
myocarditis
iron metabolism
iron deficiency
Online Access:https://www.mdpi.com/2073-4409/10/4/818

Internet

https://www.mdpi.com/2073-4409/10/4/818

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