Chemerin-induced macrophages pyroptosis in fetal brain tissue leads to cognitive disorder in offspring of diabetic dams

Chemerin-induced macrophages pyroptosis in fetal brain tissue leads to cognitive disorder in offspring of diabetic dams

Abstract Background Chemerin is highly expressed in the serum, placenta tissue, and umbilical cord blood of diabetic mother; however, the impact of chemerin on cognitive disorders of offspring from mothers with diabetes in pregnancy remains unclear. Methods A diabetic phenotype in pregnant mice dams...

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Bibliographic Details
Main Authors: Zhaoxia Liang, Luyang Han, Dianjianyi Sun, Yanmin Chen, Qi Wu, Lixia Zhang, Menglin Zhou, Danqing Chen
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Neuroinflammation
Subjects:
Chemerin
Diabetes in pregnancy
ChemR23
CCRL2
Macrophages
Pyroptosis
Online Access:http://link.springer.com/article/10.1186/s12974-019-1573-6

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http://link.springer.com/article/10.1186/s12974-019-1573-6

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