Supercooling Agent Icilin Blocks a Warmth-Sensing Ion Channel TRPV3
Transient receptor potential vanilloid subtype 3 (TRPV3) is a thermosensitive ion channel expressed in a variety of neural cells and in keratinocytes. It is activated by warmth (33–39°C), and its responsiveness is dramatically increased at nociceptive temperatures greater than 40°C. Monoterpenoids a...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1100/2012/982725 |