Massively parallel signature sequencing and bioinformatics analysis identifies up-regulation of TGFBI and SOX4 in human glioblastoma.

BACKGROUND: A comprehensive network-based understanding of molecular pathways abnormally altered in glioblastoma multiforme (GBM) is essential for developing effective therapeutic approaches for this deadly disease. METHODOLOGY/PRINCIPAL FINDINGS: Applying a next generation sequencing technology, ma...

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Bibliographic Details
Main Authors: Biaoyang Lin, Anup Madan, Jae-Geun Yoon, Xuefeng Fang, Xiaowei Yan, Taek-Kyun Kim, Daehee Hwang, Leroy Hood, Gregory Foltz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2856677?pdf=render