Valganciclovir Inhibits Human Adenovirus Replication and Pathology in Permissive Immunosuppressed Female and Male Syrian Hamsters

Adenovirus infections of immunocompromised pediatric hematopoietic stem cell transplant patients can develop into serious and often deadly multi-organ disease. There are no drugs approved for adenovirus infections. Cidofovir (an analog of 2-deoxycytidine monophosphate) is used at times but it can b...

Full description

Bibliographic Details
Main Authors: Karoly Toth, Baoling Ying, Ann E. Tollefson, Jacqueline F. Spencer, Lata Balakrishnan, John E. Sagartz, Robert Mark L. Buller, William S. M. Wold
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/7/3/1409