High sensitive detection of circulating tumor cell by multimarker lipid magnetic nanoparticles and clinical verifications

Abstract Tumor cells with heterogeneity and diversity can express different markers. At present, positive separation of circulating tumor cells (CTC) taking EpCAM as the marker was used in most cases which could be one-sided, while this study successfully prepared four antibody-modified magnetic imm...

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Bibliographic Details
Main Authors: Jingde Chen, Lin Chen, Shibin Du, Jing Wu, Ming Quan, Hua Yin, Yin Wu, Xuanting Ye, Xiaofei Liang, Hong Jiang
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12951-019-0548-1