Real‐world evidence of population differences in allopurinol‐related severe cutaneous adverse reactions in East Asians: A population‐based cohort study

Abstract Allopurinol‐related severe cutaneous adverse reactions (SCARs) are strongly associated with HLA‐B*58:01, the allele frequency (AF) of which is largely different among East Asians. However, evidence of population differences in SCAR development and relevance of genetic and/or other risk fact...

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Bibliographic Details
Main Authors: Tsugumichi Sato, Ching‐Lan Cheng, Heung‐Woo Park, Yea‐Huei Kao Yang, Min‐Suk Yang, Mizuki Fujita, Yuji Kumagai, Masahiro Tohkin, Yoshiro Saito, Kimie Sai
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12964