Adiponectin and leptin induce VCAM-1 expression in human and murine chondrocytes.

BACKGROUND: Osteoarthritis (OA) and rheumatoid arthritis (RA), the most common rheumatic diseases, are characterized by irreversible degeneration of the joint tissues. There are several factors involved in the pathogenesis of these diseases including pro-inflammatory cytokines, adipokines and adhesi...

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Bibliographic Details
Main Authors: Javier Conde, Morena Scotece, Verónica López, Rodolfo Gómez, Francisca Lago, Jesús Pino, Juan Jesús Gómez-Reino, Oreste Gualillo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3526577?pdf=render