Protective Effects of Aryl Hydrocarbon Receptor Signaling in Celiac Disease Mucosa and in Poly I:C-Induced Small Intestinal Atrophy Mouse Model

Protective Effects of Aryl Hydrocarbon Receptor Signaling in Celiac Disease Mucosa and in Poly I:C-Induced Small Intestinal Atrophy Mouse Model

Aryl hydrocarbon receptor (AhR), a transcription factor activated by a large number of natural and synthetic agents, modulates the activity of immune cells in the gut and represents an important link between the environment and immune-mediated pathologies. In this study, we investigated the role of...

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Bibliographic Details
Main Authors: Vincenzo Dinallo, Irene Marafini, Davide Di Fusco, Antonio Di Grazia, Federica Laudisi, Rami Dwairi, Omero A. Paoluzi, Giovanni Monteleone, Ivan Monteleone
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
aryl hydrocarbon receptor (AhR)
celiac disease
intestinal atrophy
inflammation
IFN-gamma
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00091/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00091/full

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