Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR
The Neurotransmitter:Sodium Symporters (NSSs) represent an important class of proteins mediating sodium-dependent uptake of neurotransmitters from the extracellular space. The substrate binding stoichiometry of the bacterial NSS protein, LeuT, and thus the principal transport mechanism, has been hea...
Main Authors: | Simon Erlendsson, Kamil Gotfryd, Flemming Hofmann Larsen, Jonas Sigurd Mortensen, Michel-Andreas Geiger, Barth-Jan van Rossum, Hartmut Oschkinat, Ulrik Gether, Kaare Teilum, Claus J Loland |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/19314 |
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