Broad-scale recombination patterns underlying proper disjunction in humans.

Although recombination is essential to the successful completion of human meiosis, it remains unclear how tightly the process is regulated and over what scale. To assess the nature and stringency of constraints on human recombination, we examined crossover patterns in transmissions to viable, non-tr...

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Bibliographic Details
Main Authors: Adi Fledel-Alon, Daniel J Wilson, Karl Broman, Xiaoquan Wen, Carole Ober, Graham Coop, Molly Przeworski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2734982?pdf=render