Reduction of NANOG Mediates the Inhibitory Effect of Aspirin on Tumor Growth and Stemness in Colorectal Cancer

Reduction of NANOG Mediates the Inhibitory Effect of Aspirin on Tumor Growth and Stemness in Colorectal Cancer

Background/Aims: Cancer stem cells (CSCs) are considered to be responsible for tumor relapse and metastasis, which serve as a potential therapeutic target for cancer. Aspirin has been shown to reduce cancer risk and mortality, particularly in colorectal cancer. However, the CSCs-suppressing effect o...

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Bibliographic Details
Main Authors: Hefei Wang, Bing Liu, Jing Wang, Jinglin Li, Ying Gong, Sisi Li, Chunli Wang, Bai Cui, Xiaoyuan Xue, Mengying Yang, Wenjun Fan, Zhijie Kang, Muhammad Kamran, Jie Xu, Pengfei Tian, Yuanyuan Luo, Zhijie Hou, Lin Dong, Yanling Ren, Man Li, Qingping Wen, Wei Cheng, Lingzhi Xu, Ling Wang, Quentin Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Colorectal Cancer
Cancer Stem Cells
NANOG
Protein Stabilization
Aspirin
Online Access:https://www.karger.com/Article/FullText/485405

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https://www.karger.com/Article/FullText/485405

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