Identification of TSG101 functional domains and p21 loci required for TSG101-mediated p21 gene regulation.

TSG101 (tumor susceptibility gene 101) is a multi-domain protein known to act in the cell nucleus, cytoplasm, and periplasmic membrane. Remarkably, TSG101, whose location within cells varies with the stage of the cell cycle, affects biological events as diverse as cell growth and proliferation, gene...

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Bibliographic Details
Main Authors: Yu-Shiuan Lin, Yin-Ju Chen, Stanley N Cohen, Tzu-Hao Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823576?pdf=render