Acute vs. Chronic vs. Cyclic Hypoxia: Their Differential Dynamics, Molecular Mechanisms, and Effects on Tumor Progression

Hypoxia has been shown to increase the aggressiveness and severity of tumor progression. Along with chronic and acute hypoxic regions, solid tumors contain regions of cycling hypoxia (also called intermittent hypoxia or IH). Cyclic hypoxia is mimicked <i>in vitro</i> and <i>in vivo...

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Bibliographic Details
Main Authors: Kritika Saxena, Mohit Kumar Jolly
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/8/339