Contraction of basal filopodia controls periodic feather branching via Notch and FGF signaling

Contraction of basal filopodia controls periodic feather branching via Notch and FGF signaling

Keratinocytes are organised into a periodic pattern in feather branching, but how this is regulated is unclear. Here, the authors show that there is a coordinated change in cell shape and adherence, mediated by Notch, FGF signalling and Rho GTPases, which in turn regulates feather branching.

Bibliographic Details
Main Authors: Dongyang Cheng, Xiaoli Yan, Guofu Qiu, Juan Zhang, Hanwei Wang, Tingting Feng, Yarong Tian, Haiping Xu, Meiqing Wang, Wanzhong He, Ping Wu, Randall B Widelitz, Cheng-Ming Chuong, Zhicao Yue
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03801-z

Internet

https://doi.org/10.1038/s41467-018-03801-z

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