Several different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population.

Adult-type hypolactasia is a common phenotype caused by the lactase enzyme deficiency. The -13910 C>T polymorphism, located 14 Kb upstream of the lactase gene (LCT) in the MCM6 gene was associated with lactase persistence (LP) in Europeans. This polymorphism is rare in Africa but several other va...

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Bibliographic Details
Main Authors: Deise C Friedrich, Sidney E B Santos, Ândrea K C Ribeiro-dos-Santos, Mara H Hutz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3460917?pdf=render