Curcumin Reinforces MiR-29a Expression, Reducing Mesangial Fibrosis in a Model of Diabetic Fibrotic Kidney via Modulation of CB1R Signaling

Curcumin Reinforces MiR-29a Expression, Reducing Mesangial Fibrosis in a Model of Diabetic Fibrotic Kidney via Modulation of CB1R Signaling

Renal fibrosis is a hallmark event in the pathogenesis of diabetic nephropathy. Considerable evidence now supports that multiple intracellular signaling pathways are critically involved in renal fibrosis. Previously, our studies have shown that dysregulation of the MicroRNA 29a (miR-29a)- or cannabi...

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Bibliographic Details
Main Authors: Yung-Chien Hsu, Pey-Jium Chang, Shih-Jiun Lin, Chia-Ching Liaw, Ya-Hsueh Shih, Lee-Wen Chen, Chun-Liang Lin
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Processes
Subjects:
mesangial fibrosis
curcumin
microRNA-29a
cannabinoid receptor type 1
Online Access:https://www.mdpi.com/2227-9717/9/4/694

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https://www.mdpi.com/2227-9717/9/4/694

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