Characterization of effector and memory T cell subsets in the immune response to bovine tuberculosis in cattle.

Cultured IFN-γ ELISPOT assays are primarily a measure of central memory T cell (Tcm) responses with humans; however, this important subset of lymphocytes is poorly characterized in cattle. Vaccine-elicited cultured IFN-γ ELISPOT responses correlate with protection against bovine tuberculosis in catt...

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Bibliographic Details
Main Authors: Mayara F Maggioli, Mitchell V Palmer, Tyler C Thacker, H Martin Vordermeier, W Ray Waters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4400046?pdf=render