Natural Killer Defective Maturation Is Associated with Adverse Clinical Outcome in Patients with Acute Myeloid Leukemia

Natural Killer Defective Maturation Is Associated with Adverse Clinical Outcome in Patients with Acute Myeloid Leukemia

Accumulating evidence highlights natural killer (NK) cell parameters as potential prognostic factors in cancer patients, which provides a strong rationale for developing therapeutic strategies aiming at restoring NK cell. However, reaching this point warrants better characterization of tumor-induced...

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Bibliographic Details
Main Authors: Anne-Sophie Chretien, Cyril Fauriat, Florence Orlanducci, Claire Galseran, Jerome Rey, Gaelle Bouvier Borg, Emmanuel Gautherot, Samuel Granjeaud, Jean-François Hamel-Broza, Clemence Demerle, Norbert Ifrah, Catherine Lacombe, Pascale Cornillet-Lefebvre, Jacques Delaunay, Antoine Toubert, Emilie Gregori, Herve Luche, Marie Malissen, Christine Arnoulet, Jacques A. Nunes, Norbert Vey, Daniel Olive
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Immunology
Subjects:
acute myeloid leukemia
prognostic biomarkers
natural killer
natural killer maturation
mass cytometry
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00573/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00573/full

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