Continuous-flow enantioselective α-aminoxylation of aldehydes catalyzed by a polystyrene-immobilized hydroxyproline

Continuous-flow enantioselective α-aminoxylation of aldehydes catalyzed by a polystyrene-immobilized hydroxyproline

The application of polystyrene-immobilized proline-based catalysts in packed-bed reactors for the continuous-flow, direct, enantioselective α-aminoxylation of aldehydes is described. The system allows the easy preparation of a series of β-aminoxy alcohols (after a reductive workup) with excellent op...

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Bibliographic Details
Main Authors: Xacobe C. Cambeiro, Rafael Martín-Rapún, Pedro O. Miranda, Sonia Sayalero, Esther Alza, Patricia Llanes, Miquel A. Pericàs
Format: Article
Language:English
Published: Beilstein-Institut 2011-10-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
α-aminoxylation
continuous flow
packed-bed reactors
polystyrene-immobilized catalysts
proline
Online Access:https://doi.org/10.3762/bjoc.7.172

Internet

https://doi.org/10.3762/bjoc.7.172

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