Inhibitory effect of Erinacines A on the growth of DLD-1 colorectal cancer cells is induced by generation of reactive oxygen species and activation of p70S6K and p21

Inhibitory effect of Erinacines A on the growth of DLD-1 colorectal cancer cells is induced by generation of reactive oxygen species and activation of p70S6K and p21

Hericium erinaceus is a well-known edible mushroom with valuable biological properties. Erinacine A is the major active agent of the diterpenoid compounds of the cultured mycelia of H. erinaceus. This agent has multiple physiological activities, including anti-tumourigenic activity. In this study, w...

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Bibliographic Details
Main Authors: Chien-Chang Lu, Wen-Shih Huang, Kam-Fai Lee, Ko-Chao Lee, Meng-Chiao Hsieh, Cheng-Yi Huang, Li-Ya Lee, Bih-O. Lee, Chih-Chuan Teng, Chien-Heng Shen, Shui-Yi Tung, Hsing-Chun Kuo
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Journal of Functional Foods
Subjects:
H. erinaceus
Erinacines A
Colorectal cancer cells
ROS
p70S6K
p21
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615006350

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http://www.sciencedirect.com/science/article/pii/S1756464615006350

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