Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway.

Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway.

Hydrogen sulfide (H(2)S) has been shown to protect against oxidative stress injury and inflammation in various hypoxia-induced insult models. However, it remains unknown whether H(2)S protects human skin keratinocytes (HaCaT cells) against chemical hypoxia-induced damage. In the current study, HaCaT...

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Bibliographic Details
Main Authors: Chuntao Yang, Zhanli Yang, Meifen Zhang, Qi Dong, Xiuyu Wang, Aiping Lan, Fanqin Zeng, Peixi Chen, Chuhuai Wang, Jianqiang Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3136491?pdf=render

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http://europepmc.org/articles/PMC3136491?pdf=render

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