Evolutionary constraint and disease associations of post-translational modification sites in human genomes.
Interpreting the impact of human genome variation on phenotype is challenging. The functional effect of protein-coding variants is often predicted using sequence conservation and population frequency data, however other factors are likely relevant. We hypothesized that variants in protein post-trans...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC4303425?pdf=render |