Phagocytosis escape by a Staphylococcus aureus protein that connects complement and coagulation proteins at the bacterial surface.

Phagocytosis escape by a Staphylococcus aureus protein that connects complement and coagulation proteins at the bacterial surface.

Upon contact with human plasma, bacteria are rapidly recognized by the complement system that labels their surface for uptake and clearance by phagocytic cells. Staphylococcus aureus secretes the 16 kD Extracellular fibrinogen binding protein (Efb) that binds two different plasma proteins using sepa...

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Bibliographic Details
Main Authors: Ya-Ping Ko, Annemarie Kuipers, Claudia M Freitag, Ilse Jongerius, Eva Medina, Willemien J van Rooijen, András N Spaan, Kok P M van Kessel, Magnus Höök, Suzan H M Rooijakkers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3861539?pdf=render

Internet

http://europepmc.org/articles/PMC3861539?pdf=render

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