Pro-inflammatory Effect of Downregulated CD73 Expression in EAE Astrocytes

Pro-inflammatory Effect of Downregulated CD73 Expression in EAE Astrocytes

CD73, an ectonucleotidase, participates in the regulation of immune responses by controlling the conversion of extracellular AMP to adenosine. In this study, we investigated whether any type of brain cells, especially neuroglia cells, exhibit altered CD73 expression, localization or activity upon ex...

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Bibliographic Details
Main Authors: Shumin Zhou, Guoping Liu, Jie Guo, Fanqiang Kong, Song Chen, Zhiyun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
astrocytes
CD73
EAE
downregulation
adenosine
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00233/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00233/full

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