RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin

RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin

Heterochromatin formed by the SUV39 histone methyltransferases represses transcription from repetitive DNA sequences and ensures genomic stability. How SUV39 enzymes localize to their target genomic loci remains unclear. Here, we demonstrate that chromatin-associated RNA contributes to the stable as...

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Bibliographic Details
Main Authors: Whitney L Johnson, William T Yewdell, Jason C Bell, Shannon M McNulty, Zachary Duda, Rachel J O’Neill, Beth A Sullivan, Aaron F Straight
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
heterochromatin
noncoding RNA
histone methylation
SUV39H1
chromatin
Online Access:https://elifesciences.org/articles/25299

Internet

https://elifesciences.org/articles/25299

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