Synergistic Cytotoxic Effects of Resveratrol in Combination with Ceramide Metabolizing Enzymes in Ph + Acute Lymphoblastic Leukemia

Bioactive sphingolipids are a lipid family including ceramide, sphingosine-1-phosphate (S1P) and glucosyl ceramide (GC). Ceramide produced through de novo synthesis pathway (Serine Palmitoyl Transferase (SPT) is a key enzyme subjected to regulation) plays significant roles in the induction of apopto...

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Bibliographic Details
Main Authors: Osman Oğuz, Aysun Adan
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Proceedings
Subjects:
Online Access:https://www.mdpi.com/2504-3900/1/10/984