Targeted Genomic Screen Reveals Focal Long Non-Coding RNA Copy Number Alterations in Cancer Cell Lines

Targeted Genomic Screen Reveals Focal Long Non-Coding RNA Copy Number Alterations in Cancer Cell Lines

The landscape of somatic copy-number alterations (SCNAs) affecting long non-coding RNAs (lncRNAs) in human cancers remains largely unexplored. While the majority of lncRNAs remain to be functionally characterized, several have been implicated in cancer development and metastasis. Considering the ple...

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Bibliographic Details
Main Authors: Pieter-Jan Volders, Steve Lefever, Shalina Baute, Justine Nuytens, Katrien Vanderheyden, Björn Menten, Pieter Mestdagh, Jo Vandesompele
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Non-Coding RNA
Subjects:
lncRNA
long non-coding RNA
array CGH
somatic copy-number alterations
Online Access:http://www.mdpi.com/2311-553X/4/3/21

Internet

http://www.mdpi.com/2311-553X/4/3/21

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