Impact of autophagy on chemotherapy and radiotherapy mediated tumor cytotoxicity: "to live or not to live"

Autophagy, a highly regulated cell "self-eating" pathway, is controlled by the action of over 34 autophagy-related proteins (collectively termed Atgs). Although they are fundamentally different processes, autophagy and apoptosis (type I programmed cell death), under certain circums...

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Bibliographic Details
Main Authors: Xuehuo eZeng, Timothy James Kinsella
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2011.00030/full