ER stress activation in the intestinal mucosa but not in mesenteric adipose tissue is associated with inflammation in Crohn's disease patients.

ER stress activation in the intestinal mucosa but not in mesenteric adipose tissue is associated with inflammation in Crohn's disease patients.

Chronic/abnormal activation of endoplasmic reticulum (ER) stress is linked to the exacerbation of the inflammatory process and has been recently linked to Crohn's disease (CD) pathophysiology. We investigated the intestinal mucosa and the mesenteric adipose tissue (MAT) collected from CD patien...

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Main Authors: Andressa Coope, Lívia Bitencourt Pascoal, José Diego Botezelli, Francesca Aparecida Ramos da Silva, Maria de Lourdes Setsuko Ayrizono, Bruno Lima Rodrigues, Marciane Milanski, Rita Barbosa Carvalho, João José Fagundes, Lício Augusto Velloso, Raquel Franco Leal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223105

Internet

https://doi.org/10.1371/journal.pone.0223105

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