A novel method for sample preparation of fresh lung cancer tissue for proteomics analysis by tumor cell enrichment and removal of blood contaminants

<p>Abstract</p> <p>Background</p> <p>In-depth proteomics analyses of tumors are frequently biased by the presence of blood components and stromal contamination, which leads to large experimental variation and decreases the proteome coverage. We have established a reprod...

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Bibliographic Details
Main Authors: Orre Lotta, Bergman Per, Elmberger Göran, Pernemalm Maria, De Petris Luigi, Lewensohn Rolf, Lehtiö Janne
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Proteome Science
Online Access:http://www.proteomesci.com/content/8/1/9