Pharmacokinetic and pharmacodynamic comparison of subcutaneous intramuscular leuprolide acetate formulations in male subjects

Background: The aim of this study was to compare the pharmacokinetics (PK) and pharmacodynamics (PD) of two distinct formulations of leuprolide acetate (LA); subcutaneous (SC) injection and intramuscular (IM) injection. Methods: A total of 32 healthy men were randomized to receive a single 7.5 mg in...

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Bibliographic Details
Main Authors: Daniel Saltzstein, Neal D. Shore, Judd W. Moul, Franklin Chu, Raoul Concepcion, Stephan de la Motte, John A. McLane, Stuart Atkinson, Alex Yang, E. David Crawford
Format: Article
Language:English
Published: SAGE Publishing 2018-02-01
Series:Therapeutic Advances in Urology
Online Access:https://doi.org/10.1177/1756287217738150