Discrepancy of glutamic acid decarboxylase 65 autoantibody results between RSR radioimmunoassay and enzyme‐linked immunosorbent assay in patients with type 1 diabetes is related to autoantibody affinity

Discrepancy of glutamic acid decarboxylase 65 autoantibody results between RSR radioimmunoassay and enzyme‐linked immunosorbent assay in patients with type 1 diabetes is related to autoantibody affinity

Abstract Aim/Introduction Autoantibodies to the 65 kDa isoform of glutamic acid decarboxylase (GADA) are a valuable diagnostic and predictive marker for type 1 diabetes. Recently, it has been reported that a significant proportion of sera in the commercial RSR radioimmunoassay (RIA) that have tested...

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Bibliographic Details
Main Authors: Eiji Kawasaki, Akira Okada, Aira Uchida, Takahiro Fukuyama, Yoko Sagara, Yuko Nakano, Hidekazu Tamai, Masayuki Tojikubo, Nobuhiko Koga
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:Journal of Diabetes Investigation
Subjects:
Affinity
Anti‐glutamic acid decarboxylase antibody
Enzyme‐linked immunosorbent assay
Online Access:https://doi.org/10.1111/jdi.12996

Internet

https://doi.org/10.1111/jdi.12996

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