Mesenchymal stromal cells primed with paclitaxel provide a new approach for cancer therapy.

BACKGROUND: Mesenchymal stromal cells may represent an ideal candidate to deliver anti-cancer drugs. In a previous study, we demonstrated that exposure of mouse bone marrow derived stromal cells to Doxorubicin led them to acquire anti-proliferative potential towards co-cultured haematopoietic stem c...

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Bibliographic Details
Main Authors: Augusto Pessina, Arianna Bonomi, Valentina Coccè, Gloria Invernici, Stefania Navone, Loredana Cavicchini, Francesca Sisto, Maura Ferrari, Lucia Viganò, Alberta Locatelli, Emilio Ciusani, Graziella Cappelletti, Daniele Cartelli, Caruso Arnaldo, Eugenio Parati, Giovanni Marfia, Roberto Pallini, Maria Laura Falchetti, Giulio Alessandri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3243689?pdf=render