Contrasting Nephropathic Responses to Oral Administration of Extract of Cultured Penicillium polonicum in Rat and Primate

Liquid- or solid substrate-cultured Penicillium polonicum administered in feed to rats over several days evokes a histopathological response in kidney involving apoptosis and abnormal mitosis in proximal tubules. The amphoteric toxin is yet only partly characterized, but can be isolated from culture...

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Bibliographic Details
Main Authors: John E. Fincham, Katharine M. McHugh, Peter G. Mantle
Format: Article
Language:English
Published: MDPI AG 2010-08-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/2/8/2083/