Classes of Drugs that Mitigate Radiation Syndromes

Classes of Drugs that Mitigate Radiation Syndromes

We previously reported several vignettes on types and classes of drugs able to mitigate acute and, in at least one case, late radiation syndromes in mice. Most of these had emerged from high throughput screening (HTS) of bioactive and chemical drug libraries using ionizing radiation-induced lymphocy...

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Bibliographic Details
Main Authors: Ewa D. Micewicz, Robert D. Damoiseaux, Gang Deng, Adrian Gomez, Keisuke S. Iwamoto, Michael E. Jung, Christine Nguyen, Andrew J. Norris, Josephine A. Ratikan, Piotr Ruchala, James W. Sayre, Dörthe Schaue, Julian P. Whitelegge, William H. McBride
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
radiation mitigators
hematopoietic acute radiation syndrome
gastro-intestinal acute radiation syndrome
delayed effects of radiation exposure
multi-organ disease syndrome
High throughput screening
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.666776/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.666776/full

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