Evaluation of the Reversal of Multidrug Resistance by Ribonucleic Acid Interference in a Human Colon Cancer Model Using a Luciferase Reporter Gene and Coelenterazine
The reversal effect of multidrug resistance ( MDR1 ) gene expression by adenoviral vector-mediated MDR1 ribonucleic acid interference was assessed in a human colon cancer animal model using bioluminescent imaging with Renilla luciferase (Rluc) gene and coelenterazine, a substrate for Rluc or MDR1 ge...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi - SAGE Publishing
2010-11-01
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| Series: | Molecular Imaging |
| Online Access: | https://doi.org/10.2310/7290.2010.00021 |