ComHub: Community predictions of hubs in gene regulatory networks

ComHub: Community predictions of hubs in gene regulatory networks

Abstract Background Hub transcription factors, regulating many target genes in gene regulatory networks (GRNs), play important roles as disease regulators and potential drug targets. However, while numerous methods have been developed to predict individual regulator-gene interactions from gene expre...

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Bibliographic Details
Main Authors: Julia Åkesson, Zelmina Lubovac-Pilav, Rasmus Magnusson, Mika Gustafsson
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Bioinformatics
Subjects:
Gene regulatory networks
Hubs
Master regulators
Network inference
Online Access:https://doi.org/10.1186/s12859-021-03987-y

Internet

https://doi.org/10.1186/s12859-021-03987-y

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