A chimeric IgE that mimics IgE from patients allergic to acid-hydrolyzed wheat proteins is a novel tool for in vitro allergenicity assessment of functionalized glutens.

A chimeric IgE that mimics IgE from patients allergic to acid-hydrolyzed wheat proteins is a novel tool for in vitro allergenicity assessment of functionalized glutens.

Acid-hydrolyzed wheat proteins (acid-HWPs) have been shown to provoke severe allergic reactions in Europe and Japan that are distinct from classical wheat allergies. Acid-HWPs were shown to contain neo-epitopes induced by the deamidation of gluten proteins. However, products with variable rates of d...

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Bibliographic Details
Main Authors: Olivier Tranquet, Jean-Charles Gaudin, Sarita Patil, Johanna Steinbrecher, Kayoko Matsunaga, Reiko Teshima, Shinobu Sakai, Colette Larré, Sandra Denery-Papini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5678878?pdf=render

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http://europepmc.org/articles/PMC5678878?pdf=render

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