Gene-Based Association Analysis Suggests Association of HTR2A With Antidepressant Treatment Response in Depressed Patients

Gene-Based Association Analysis Suggests Association of HTR2A With Antidepressant Treatment Response in Depressed Patients

The serotonin [5-hydroxytryptamine (5-HT)] system has been implicated in the pathogenesis of major depressive disorder (MDD). Among the 5-HT receptor subtypes, 5-HT2 is one of the major pharmacological therapeutic targets for MDD. There have been inconsistent findings in previous pharmacogenetic stu...

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Bibliographic Details
Main Authors: Chung-Feng Kao, Po-Hsiu Kuo, Younger W.-Y. Yu, Albert C. Yang, Eugene Lin, Yu-Li Liu, Shih-Jen Tsai
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
gene-based analysis
major depressive disorders
antidepressant
5-hydroxytryptamine receptor 2A
single nucleotide polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.559601/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.559601/full

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