PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells

PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells

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Summary: p21-Activated kinase 4 (PAK4), a serine/threonine kinase, is purported to localize to podosomes: transient adhesive structures that degrade the extracellular matrix to facilitate rapid myeloid cell migration. We find that treatment of transforming growth factor β (TGF-β)-differentiated mono...

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Bibliographic Details
Main Authors: Elizabeth Foxall, Adela Staszowska, Liisa M. Hirvonen, Mirella Georgouli, Mariacristina Ciccioli, Alexander Rimmer, Lynn Williams, Yolanda Calle, Victoria Sanz Moreno, Susan Cox, Gareth E. Jones, Claire M. Wells
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314871

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http://www.sciencedirect.com/science/article/pii/S2211124719314871

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