Bioactive 2(1H)-Pyrazinones and Diketopiperazine Alkaloids from a Tunicate-Derived Actinomycete Streptomyces sp.

Bioactive 2(1H)-Pyrazinones and Diketopiperazine Alkaloids from a Tunicate-Derived Actinomycete Streptomyces sp.

As a part of our ongoing effort to allocate marine microbial bioactive leads, a tunicate-derived actinomycete, Streptomyces sp. Did-27, was investigated. Three new 2(1H)-pyrazinones derivatives, (S)-6-(sec-butyl)-3-isopropylpyrazin-2(1H)-one (1), (S)-3-(sec-butyl)-6-isopropylpyrazin-2(1H)-one (2) an...

Full description

Bibliographic Details
Main Authors: Lamiaa A. Shaala, Diaa T. A. Youssef, Jihan M. Badr, Steve M. Harakeh
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Molecules
Subjects:
Red Sea Didemnum sp.
Streptomyces sp. Did-27
alkylated 2(1H)-pyrazinone derivatives
diketopiperazine alkaloids
cancer cell lines
antiproliferative and cytotoxic activities
Online Access:http://www.mdpi.com/1420-3049/21/9/1116

Internet

http://www.mdpi.com/1420-3049/21/9/1116

Similar Items