Exercise protects against diet-induced insulin resistance through downregulation of protein kinase Cβ in mice.

Physical exercise is an important and effective therapy for diabetes. However, its underlying mechanism is not fully understood. Protein kinase Cβ (PKCβ) has been suggested to be involved in the pathogenesis of obesity and insulin resistance, but the role of PKCβ in exercise-induced improvements in...

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Main Authors: Xiaoquan Rao, Jixin Zhong, Xiaohua Xu, Brianna Jordan, Santosh Maurya, Zachary Braunstein, Tse-Yao Wang, Wei Huang, Sudha Aggarwal, Muthu Periasamy, Sanjay Rajagopalan, Kamal Mehta, Qinghua Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3857188?pdf=render