Host immunity modulates the efficacy of microbiota transplantation for treatment of Clostridioides difficile infection

Host immunity modulates the efficacy of microbiota transplantation for treatment of Clostridioides difficile infection

Transfer of a host’s microbiota by faecal microbiota transplantation has shown benefit in the context of recurrent Clostridioides difficle infection. Here the authors shows the inflammatory status of the recipient can impact on engraftment and the efficacy of the introduced microbiota in a model of...

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Bibliographic Details
Main Authors: Eric R. Littmann, Jung-Jin Lee, Joshua E. Denny, Zahidul Alam, Jeffrey R. Maslanka, Isma Zarin, Rina Matsuda, Rebecca A. Carter, Bože Susac, Miriam S. Saffern, Bryton Fett, Lisa M. Mattei, Kyle Bittinger, Michael C. Abt
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20793-x

Internet

https://doi.org/10.1038/s41467-020-20793-x

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