B7-H3 Chimeric Antigen Receptor Redirected T Cells Target Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma

Potent CAR-T therapies that target appropriate antigens can benefit the treatment of anaplastic lymphoma kinase-positive (ALK<sup>+</sup>) anaplastic large cell lymphoma (ALCL), which is the most common subtype of T cell lymphoma. In this study, we observed overexpression of B7-H3 in ALC...

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Bibliographic Details
Main Authors: Zhenguo Zi, Haihong Zhao, Huanyu Wang, Xiaojing Ma, Fang Wei
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
ALK
Online Access:https://www.mdpi.com/2072-6694/12/12/3815