Elevated Expression of Lumican in Lung Cancer Cells Promotes Bone Metastasis through an Autocrine Regulatory Mechanism

<i>Background</i>: The microarray analysis of whole-genome expression indicated that the gene encoding the protein lumican, which is associated with extracellular matrix (ECM) interaction, was highly expressed in osteotropic lung cancer cell lines with an enhanced capacity of bone metast...

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Bibliographic Details
Main Authors: Kuan-Chung Hsiao, Pei-Yi Chu, Gee-Chen Chang, Ko-Jiunn Liu
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/1/233