The Glucocorticoid Receptor: A Revisited Target for Toxins

The hypothalamic-pituitary-adrenal (HPA) axis activation and glucocorticoid responses are critical for survival from a number of bacterial, viral and toxic insults, demonstrated by the fact that removal of the HPA axis or GR blockade enhances mortality rates. Replacement with synthetic glucocorticoi...

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Bibliographic Details
Main Authors: Jeanette I. Webster Marketon, Esther M. Sternberg
Format: Article
Language:English
Published: MDPI AG 2010-06-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/2/6/1357/