Adiponectin Enhances B-Cell Proliferation and Differentiation via Activation of Akt1/STAT3 and Exacerbates Collagen-Induced Arthritis

Adiponectin Enhances B-Cell Proliferation and Differentiation via Activation of Akt1/STAT3 and Exacerbates Collagen-Induced Arthritis

Although B cells have been shown to contribute to the pathogenesis of rheumatoid arthritis (RA), the precise role of B cells in RA needs to be explored further. Our previous studies have revealed that adiponectin (AD) is expressed at high levels in inflamed synovial joint tissues, and its expression...

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Bibliographic Details
Main Authors: Nan Che, Xiaoxuan Sun, Lei Gu, Xiaohui Wang, Jingjing Shi, Yi Sun, Lingxiao Xu, Rui Liu, Junke Wang, Fengyi Zhu, Na Peng, Fan Xiao, Dajun Hu, Liwei Lu, Wen Qiu, Miaojia Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
adiponectin
B cells
proliferation
differentiation
collagen-induced arthritis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.626310/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.626310/full

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