The influence of actin depolymerization induced by Cytochalasin D and mechanical stretch on interleukin-8 expression and JNK phosphorylation levels in human retinal pigment epithelial cells

The influence of actin depolymerization induced by Cytochalasin D and mechanical stretch on interleukin-8 expression and JNK phosphorylation levels in human retinal pigment epithelial cells

Abstract Background This study explores the role of actin cytoskeleton depolymerization induced by Cytochalasin D and mechanical stretch on the interleukin-8 (IL-8) expression and c-jun N-terminal kinase (JNK) phosphorylation levels in human retinal pigment epithelial (RPE) cells. Methods A Flexcell...

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Bibliographic Details
Main Authors: Meng Gao, Shen Wu, Jing Ji, JingXue Zhang, Qian Liu, YanKun Yue, Lu Liu, XinXin Liu, Wu Liu
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Ophthalmology
Subjects:
Stress
Mechanical
Retinal pigment epithelium
Cytoskeleton
Cytokines
Cytochalasin
Online Access:http://link.springer.com/article/10.1186/s12886-017-0437-z

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http://link.springer.com/article/10.1186/s12886-017-0437-z

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