Serum IgM Glycosylation Associated with Tuberculosis Infection in Mice

Serum IgM Glycosylation Associated with Tuberculosis Infection in Mice

We demonstrate that M. tuberculosis infection influenced host protein glycosylation in a mouse model. The mechanism by which infection modifies glycans in serum proteins is not understood. Investigation of the regulation of such modifications by M. tuberculosis opens a new field that could lead to t...

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Bibliographic Details
Main Authors: Tadahiro Kumagai, Ainhoa Palacios, Arturo Casadevall, M. Jesús García, Carlos Toro, Michael Tiemeyer, Rafael Prados-Rosales
Format: Article
Language:English
Published: American Society for Microbiology 2019-03-01
Series:mSphere
Subjects:
IgM
Mycobacterium tuberculosis
fucosylation
glycans
immunoglobulin M
mice
Online Access:https://doi.org/10.1128/mSphere.00684-18

Internet

https://doi.org/10.1128/mSphere.00684-18

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